Our research is focus in NP=O containing molecules – Phosphinamides. The power of this chemistry is illustrated by the structural diversity achieved just changing some parts of the molecule, or by just modifying the reaction conditions, such as solvent, temperature or base employed. Dearomatization of the aromatic ring, substitution of the benzyl group alpha with respect to the nitrogen, ortho substitution of one aromatic ring attached at the phosphorus atom, and [1,2] rearrangements providing new class of aminic substrates are examples of this rich reactivity. I’m currently supervising three talented PhD students.

Pascual Oña Burgos   [ Read more...]

Diastereo- and Enantioselective alpha lithiation of benzyl diphenylphosphinamides.
Phthalocyanine chemistry towards new phosphite and phosphate sensors.

Cristinel-Adrian Popovici   [ Read more...]

Diastereo- and Enantioselective ortho lithiation of dialkyl diphenylphosphinamides.
Development of new (-)-sparteine surrogates as chiral auxiliaries

Hajar el Hajjouji   [ Read more...]

Diastereo- and Enantioselective [1,2] Aza-Wittig rearrangements of benzyl diphenylphosphinamides.
Development of new phosphinamidic stannanes molecules and their use as group transfer reagents.